Addiction and drug use is a phenomenon that challenges the future of the country in various dimensions. For this purpose, studying and planning in order to deal with this social problem requires knowing and investigating the factors affecting the prevalence of drug use. The present research was conducted to recognize and prioritize the factors affecting addiction and drug use in the rural areas of Bonab villages, Zanjan province. The current study is applied in terms of purpose and the method of doing it is descriptive-analytical and data collection based on library and field methods.The statistical population of the research is the heads of households living in the village and addicted people. Due to the high number of villages in the studied village, which was 25 inhabited villages, 10 villages were selected through cluster sampling, and based on the number of population, the number of samples for each population class was determined. The reliability of the questionnaire was confirmed using Cronbach's alpha coefficient (0.72). The findings of the research showed that based on the perspective of the statistical population, the most important effective factors in preventing drug addiction are the supervision of families, creating and diversifying job opportunities, and also the development of leisure facilities. A setof factors play a role in the occurrence and spread of drug use in villages, including individual factors, family education system, economic- Social, and finally cultural factor mentioned